how to use certain number of numbers and letters for calculation

[slyexe]

if you know the positions of each digit and capital letter then yes the first method is all you would need to do. Otherwise, if you do not know the position you would have to do either a custom mask including the full keyspace or individualize it into multiple attacks using an hcmask.

Code:

hashcat -a 3 -m 22000 -1 ?d?u hash.file ?1?1?1?1?1?1?1?1?1?1

Otherwise using a hcmask file you would include ALL possibilities with all positions of your upper case letters.

?u?u?u?d?d?d?d?d?d?d
?u?d?u?u?d?d?d?d?d?d
?u?d?d?u?u?d?d?d?d?d

etc.etc.etc...

Having such a big keyspace for a slower hash with WPA is not ideal, unfortunately this is your only options.