A bit help needed

[Flomac]

Thing is I thought those Strix cards are also reliable, If you take a look at their page:

"Industry-only 100% Automated Production Process
All ASUS graphics cards are now produced using Auto-Extreme Technology, an industry-exclusive, 100% automated production process that incorporates premium materials to set a new standard of quality."

"Patented Wing-Blade IP5X-Certified Fans for maximum airflow and longer fan lifespan."
And so on ....  
All this could just be marketing as you say of course.

It is. I can give you an example: The bearing of the cooler fan. There is ball bearing and sleeve bearing. The latter one is less noisy, which makes a good figure in game tests with noise level 2-3db down. But it weares out pretty fast when running constantly at high temps. When the fan runs out of lubrication you might not even hear it. The sudden stop of the fan will overheat the card and you can be glad if it does not start a fire. The card might be ruined and the manufacturer will usually not cover for this.
Of course you never know what kind of bearing the OEMs use and it might be even fine. But when spending 20k you might be also interested to reduce the risk of such a fatal failure.

So you say x1 is fine in most cases but MD5 for example would suffer. Can you give some kind of estimate by how much?

No, I meant fast hashes suffer where you constantly feed them with external data. MD5 with a rule-based attack and a big ruleset will be fine.